We are interested in the utilization of CT imaging to explore lung disease etiology and subtypes. Of specific interest is quantitative CT based assessment of chronic obstructive pulmonary disease (COPD), and the relationship to lung cancer risk

^{Uthoff JM, Mott SL, Larson J, Neslund-Dudas CM, Schwartz AG, Sieren JC; and the COPDGene Investigators. Computed Tomography Features of Lung Structure Have Utility for Differentiating Malignant and Benign Pulmonary Nodules. Chronic Obstr Pulm Dis. 2022 Apr 29;9(2):154-164. doi: 10.15326/jcopdf.2021.0271. PMID: 35021316.}

^{Strand M, Austin E, Moll M, Pratte KA, Regan EA, Hayden LP, Bhatt SP, Boriek AM, Casaburi R, Silverman EK, Fortis S, Ruczinski I, Koegler H, Rossiter HB, Occhipinti M, Hanania NA, Gebrekristos HT, Lynch DA, Kunisaki KM, Young KA, Sieren JC, Ragland M, Hokanson JE, Lutz SM, Make BJ, Kinney GL, Cho MH, Pistolesi M, DeMeo DL, Sciurba FC, Comellas AP, Diaz AA, Barjaktarevic I, Bowler RP, Kanner RE, Peters SP, Ortega VE, Dransfield MT, Crapo JD. A Risk Prediction Model for Mortality Among Smokers in the COPDGene® Study. Chronic obstructive pulmonary diseases 2020 Oct;7(4):346-361. doi: 10.15326/jcopdf.7.4.2020.0146. PubMed PMID: 32877963; PubMed Central PMC7883903}

^{Lusk CM, Wenzlaff AS, Watza D, Sieren JC, Robinette N, Walworth G, Petrich M, Neslund-Dudas C, Flynn MJ, Song T, Spizarny D, Simoff MJ, Soubani AO, Gadgeel S, Schwartz AG. Quantitative imaging markers of lung function in a smoking population distinguish COPD sub-groups with differential lung cancer risk. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2019. Apr;28(4):724-730. doi: 10.1158/1055-9965.EPI-18-0886. Epub 2019/01/14. PubMed PMID: 30642838; PMCID: PMC6449213.}

^{Carr LL, Jacobson S, Lynch DA, Foreman MG, Flenaugh EL, Hersh CP, Sciurba FC, Wilson DO, Sieren JC, Mulhall P, Kim V, Kinsey CM, Bowler RP. Features of COPD as Predictors of Lung Cancer. Chest. 2018;153(6):1326-35. Epub 2018/02/17. doi: 10.1016/j.chest.2018.01.049. PubMed PMID: 29452098; PMCID: PMC6026288.}